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Secondary hyperparathyroidism (SHPT) is a common complication of Chronic kidney disease (CKD), which is mainly manifested by the overproduction of Parathyroid hormone (PTH), leading to multi-system pathologies...
Immunoglobulin A nephropathy (IgAN) is one of the most common forms of primary glomerulonephritis (GN) worldwide. While specific treatment differs regionally, treatment usually focuses on background therapy, w...
This study aimed to develop and validate a nomogram to predict the risk of peritoneal dialysis-associated peritonitis (PDAP) in patients undergoing peritopreneal dialysis.
Maintenance hemodialysis (MHD) patients often suffer from sarcopenia, affecting lower limb muscle strength and increasing the risk of falls and mortality. This study aims to develop an auxiliary screening mode...
While the appearance of red clots in the dialyzer and the arterial and venous blood tubing lines is a common phenomenon in every hemodialysis unit, the occurrence of recurrent yellowish-white matter formation ...
Type 2 diabetes (T2DM) is the leading cause of chronic kidney disease (CKD) worldwide. Identifying clinical and laboratory associations with chronic kidney disease (CKD) in type 2 diabetes (T2DM) can help phys...
Oxidative stress is a driver of acute and chronic kidney injury. Selonsertib is a clinical stage antagonist of ASK1 (MAP3K5), a serine/threonine kinase that is a mediator of oxidative stress signaling pathways...
Stress-induced hyperglycemia (SIH) is a common phenomenon in acute myocardial infarction and is associated with poor prognosis. The relationship between glycemic gap (GG), a marker of SIH, and ST-segment eleva...
Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent monogenic polycystic kidney disorder, but ADPKD presented as Glomerulocystic kidney (GCK) in adults is uncommon. Thin basement membrane...
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) that can lead to end organ damage and death without treatment. The ability to rapidly distinguish aHUS from other forms of TMA is...
The original article was published in BMC Nephrology 2025 26:156
The original article was published in BMC Nephrology 2025 26:168
C3 Glomerulopathy (C3G) is an ultra-rare glomerular disease driven by dysregulation of the alternative pathway of complement. 30–50% of adult patients progress to end stage kidney disease (ESKD) within 10 year...
Nephrotic syndrome (NS) is a common kidney disorder in children, characterized by significant proteinuria, hypoalbuminemia, and peripheral edema. While glucocorticoids (GCs) are the first-line treatment for pe...
The CKD in PLHIV is highly prevalent in Jalisco. Despite its control with ART, HIV is characterized by generating low-grade inflammation events that contribute to the development and progression of CKD. Consid...
Neutrophil extracellular traps (NETs) and oxidative stress (OS) may be involved in sepsis-associated acute kidney injury (SA-AKI). The aim of this study was to identify potential regulators which modulate NETs...
Chronic Kidney disorders is a global public health problem, including in women with polycystic ovarian syndrome (PCOS), and is characterized by renal fibrosis, nephrotoxicity and glomerulonephritis, which incr...
Thrombotic microangiopathy (TMA) represents a broad spectrum of diseases. The combination of TMA with lupus nephritis (LN) is associated with worse renal outcomes and a higher mortality rate. To date, there is...
Urinary tract infections (UTIs) are the most prevalent infections among kidney transplant recipients, with recurrent cases imposing a significant financial burden due to increased hospitalizations and treatmen...
Patients with chronic kidney disease (CKD) have a high prevalence of cerebrovascular disease and cognitive impairment. The objective was to analyse whether plasma concentrations of neurofilament light chain (N...
Diabetic nephropathy (DN) is a serious microvascular complication that can progress to end-stage renal disease, with its prevalence and associated mortality increasing globally. However extensive research, the...
Infections in renal transplant recipients (RTRs) carry great risk of morbidity-mortality, and the risk of graft loss. Concomitant infections, although common in immunosuppressed patients, should be highly susp...
This study aimed to re-evaluate the prognostic value of inflammation and nutrition-related indices in a large multicenter cohort of hemodialysis patients from 138 dialysis centers in Beijing.
Hyperkalemia is a frequent life-threatening condition in hemodialysis (HD) patients. Data comparing the usage of various K + binders in HD patients is still scarce. This study aimed to compare the efficacy and...
Fatigue among patients with end-stage kidney disease (ESKD) undergoing hemodialysis significantly impacts quality of life and anticipated treatment results. This study explores how Omani patients undergoing he...
Living donor kidney transplantation (LDKT) is a complex medical procedure requiring extensive education for both donors and transplant candidates. With technological advances in healthcare, video educational r...
To evaluate the effectiveness of a Shared Decision-Making (SDM) program in reducing unplanned dialysis among patients with advanced chronic kidney disease (CKD) and to identify factors predictive of unplanned ...
This study aimed to develop a nomogram to predict peritoneal dialysis (PD) adequacy in incident PD patients and identify those at high risk for low Kt/Vurea PD function.
End-stage renal disease (ESRD) is associated with significant morbidity and mortality, with patients often experiencing micronutrient deficiencies due to dialysis treatments. Hemodiafiltration with Endogenous ...
Due to a shortage of cadaveric organs for transplantation, some Saudi patients seek to purchase kidneys in other countries. However, kidney transplantation (KT) abroad is often associated with negative outcome...
When an adult patient lacks decision-making capacity, care decisions must be made on their behalf in their “best interests”. We know little about the experiences of the family members of adult kidney patients ...
This is a scoping review of the evidence for the use of the Patient Self-Management Assessment Tool for Hypertension (PAT) in people with hypertension. This review examines the content features, reliability, a...
Herpes- and polyomaviruses are major opportunistic pathogens after renal transplantation. Despite established guidelines, there is limited data on transplant centers’ prophylaxis and monitoring strategies and ...
Hyperlactatemia is common in intensive care unit (ICU) patients. The aim of our retrospective observational study was to analyse the impact of serum lactate on admission on mortality in patients with acute kid...
Low physical activity (LPA) is a major contributor to the global burden of chronic kidney disease (CKD). Our goal was to assess the spatiotemporal trends in the CKD burden attributable to LPA from 1990 to 2021...
Maintenance hemodialysis patients experience high morbidity and mortality, primarily from cardiovascular and infectious diseases. It was discovered recently that low arterial oxygen saturation (SaO2) is associate...
Potassium binders mitigate hyperkalemia, allowing patients to maintain their renin-angiotensin-aldosterone-system inhibitor (RAASi) treatment. This study characterized patients treated with first- or second-ge...
Post-traumatic growth is regarded as a screening indicator for quality of life of hemodialysis patients. Interpersonal relationships and forgiveness of hemodialysis patients may play an important role in impro...
Chronic kidney disease (CKD), hypertension, and diabetes are associated with dementia, and insulin resistance promotes vascular dysfunction resulting in dementia. However, the study of insulin use in preventin...
Chronic kidney disease (CKD) is a significant global health issue associated with cardiovascular risk, elevated morbidity and mortality rates, reduced quality of life, and high medical costs. Self-care behavio...
Persistent controversies surround the treatment of Immunoglobulin A nephropathy (IgAN), necessitating the exploration of safer and more effective therapeutic agents. Tripterygium wilfordii, a traditional Chine...
Sepsis-associated acute kidney injury (AKI) presents a significant clinical challenge, necessitating the identification of predictive indicators for early detection and intervention. This retrospective case-co...
Emphysematous pyelonephritis (EPN) is a necrotizing infection characterized by the production of gas in the renal parenchyma, collecting system or perirenal tissue. The treatment strategy, especially for surgi...
The incidence of clear cell renal cell carcinoma (ccRCC) has steadily increased over the past decade, and recent studies have linked bile acid (BA) metabolism to its development. However, the metabolic profile...
In critically ill elderly patients, malnutrition is a common comorbidity. The Geriatric Nutritional Risk Index (GNRI) is a straightforward tool for evaluating the nutritional status of elderly individuals. The...
Kidney failure is associated with a high symptom burden, yet few studies describe real-world management approaches.
Hospital readmission following renal transplantation significantly impacts patient outcomes and healthcare resources. While machine learning approaches offer promising solutions for risk prediction, their clin...
In patients undergoing hemodialysis, functional dependence has increasingly been recognized as a critical factor influencing both quality of life and clinical outcomes. This study evaluates the combined effect...
Cytokine-induced apoptosis inhibitor 1 (CIAPIN1) is a crucial anti-apoptotic protein; however, its role and associated molecular pathways in ferroptosis remain largely unexplored. This study aimed to investiga...
BMC Nephrology is affiliated with the UK Kidney Association
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