Table 2 Baseline laboratory data of both groups
Group A (PLEX) (n = 50) | Group B (CYC) (n = 50) | p value | |
|---|---|---|---|
Laboratory data (mean ± SD) | |||
Urea (mg/dL) median (IQR) | 37.5(10–182) | 30(10–110) | 0.638 |
Creatinine (mg/dL) | 1.4 ± 0.7 | 1.2 ± 0.6 | 0.208 |
Uric acid (mg/dL) | 5.1 ± 1.1 | 5.3 ± 1.2 | 0.402 |
ALT (U/L) median (IQR) | 18(7-170) | 20(6–84) | 0.958 |
AST (U/L) median (IQR) | 24.5(7-121) | 21.5(5–78) | 0.170 |
Hb (gm/L) | 10.6 ± 2.9 | 10.7 ± 3 | 0.857 |
WBCs (x10₃)/L | 7.3 ± 2.1 | 7.3 ± 2.2 | 0.944 |
Platelet (x10₃)/L | 65.6 ± 19.0 | 49.5 ± 19.0 | < 0.001 |
LDH (U/L) | 873.8 ± 169.3 | 782.6 ± 157.4 | 0.006 |
Fragmented RBCs % | 5.8 ± 1.2 | 4.8 ± 1.2 | < 0.001 |
Total Cholesterol (mg/dL) | 186.9 ± 44.2 | 185.4 ± 34.0 | 0.850 |
LDL-c (mg/dL) | 118.2 ± 33.7 | 112.2 ± 28.7 | 0.339 |
HDL-c (mg/dL) | 48.1 ± 14 | 44.4 ± 11.1 | 0.149 |
TG (mg/dL) | 126 ± 58.7 | 145.2 ± 49.6 | 0.080 |
Ca (mg/dL) | 8.9 ± 0.6 | 9 ± 0.6 | 0.282 |
Phosphorus (mg/dL) | 3.6 ± 0.6 | 4 ± 0.5 | < 0.001 |
CRP (mg/dL) | 5.9 ± 11.2 | 3.4 ± 4.2 | 0.137 |
Urinary protein (gm/24hrs) | 2.9 ± 0.7 | 3.3 ± 0.6 | 0.015 |
Urine sediment, number (%) | |||
Free | 23(46.0) | 0(0.0) | < 0.001 |
Granular cast | 14(28.0) | 22(44.0) | |
Red cell cast | 13(26.0) | 28(56.0) | |
Immunological profile, number (%) | |||
Serum C3 (mg/dL) (mean ± SD) | 82.3 ± 28.4 | 95.4 ± 41.8 | 0.071 |
Serum C4 (mg/dL) (mean ± SD) | 11.6 ± 8.7 | 11.9 ± 8.8 | 0.904 |
Anti Cardiolipin IgG (U/ml) | 5(10.0) | 6(12.0) | 0.749 |
Anti Cardiolipin IgM (U/ml) | 6(12.0) | 5(10.0) | 0.749 |
Lupus anticoagulant | 3(6.0) | 3(6.0) | 1.000 |