Fig. 2
From: Calycosin ameliorates albuminuria in nephrotic syndrome by targeting Notch1/Snail pathway
Calycosin alleviates glomerular structural damage and podocyte injury. After the euthanasia of rats in four experimental groups, renal cortex tissues were harvested. (A) Hematoxylin-eosin staining was performed to evaluate glomerular structural damage. Yellow arrows: inflammatory cell infiltration. Black arrows: the thickened basement membrane. Blue arrows: mesangial cell expansion. Red arrows: immunological complex deposition. (B) Areas of kidney histology damage was quantified based on the representative images of hematoxylin-eosin staining. (C) Transmission electron microscopy was used to observe podocyte structure. (D) Podocyte foot process was measured using the electron microscope to evaluate the degree of fusion. *p < 0.05, ***p < 0.001 versus control group; ##p < 0.01, ###p < 0.001 versus model group