Cumulative-incidence-rate (%) [95%-CI] | Incidence (no.) | Median time to first detection (IQR) | |
---|---|---|---|
General outcome | |||
Death | 1.7 [1.10;2.80] | 18 | 141 (66–275) |
Graft loss | 2.3 [1.60;3.50] | 24 | 155 (82–223) |
Biopsy proven acute rejection (all) | 21.4 [18.90;24.00] | 218 | 90 (30–163) |
Biopsy proven acute rejection (without borderline) | 10.0 [8.30;12.00] | 101 | 133 (77–187) |
T-cell mediated rejection | 9.5 [7.90;11.50] | 97 | 135 (78–188) |
Banff IA | 3.5 [2.50;4.80] | 34 | 121 (86–182) |
Banff IB | 1.2 [0.70;2.20] | 12 | 130 (92–184) |
Banff IIA | 3.8 [2.70;5.20] | 37 | 135 (77–185) |
Banff IIB | 1.2 [0.70;2.20] | 12 | 102 (70–168) |
Banff III | 0.2 [0.10;0.80] | 2 | 143 (139-147) |
Antibody-mediated rejection | 0.7 [0.03;0.015] | 7 | 189 (100–271) |
Borderline rejection | 14.2 [12.2;16.5] | 147 | 79 (20–138) |
Infections | |||
Herpes/Polyomaviruses | 26.6 [24.1;29.4] | 269 | 119 (76–188) |
Herpesviruses | 16.7 [14.6;19.2] | 169 | 129 (71–208) |
CMV | 14.3 [12.3;16.6] | 144 | 138 (77–219) |
D+/R- | 28.6 [22.9;35.6] | 57 | 119 (90–160) |
D+/R+ | 13.6 [10.4;17.8] | 46 | 176 (117–255) |
D-/R+ | 15.1 [10.8;21.0] | 30 | 131 (56–181) |
D-/R- | 1.8 [0.7;4.8] | 4 | 94 (38–167) |
Other herpesviruses | 3.0 [2.2;4.3] | 31 | 90 (45–145) |
HSV-1 | 1.5 [0.9;2.5] | 15 | 90 (42–148) |
VZV | 0.9 [0.5;1.7] | 9 | 93 (53–152) |
HSV-2 | 0.6 [0.3;1.3] | 6 | 90 (60–180) |
EBV | 0.7 [0.3;1.4] | 7 | 123 (95–158) |
HHV-6 | 0.1 - | 1 | - |
Polyomaviruses | 13.2 [11.2;15.4] | 132 | 108 (78–174) |
BKV | 13.2 [11.2;15.4] | 132 | 108 (78–174) |
JCV | 0.1 [-] | 1 | - |
Other infections | |||
Bacterial infection | 41.7 [38.8;44.8] | 428 | 30 (10–85) |
Fungal infection | 4.7 [3.6;6.2] | 48 | 52 (17–140) |